Status:
UNKNOWN
Neuroeconomics of Social Behavior Following Trauma Exposure
Lead Sponsor:
Mclean Hospital
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Posttraumatic Stress Disorder
Eligibility:
FEMALE
18-45 years
Brief Summary
This study will use a neuroeconomic paradigm with state-of-the-art imaging protocols to probe abnormal social reward processing underlying social withdrawal in symptomatic trauma-exposed women. By als...
Detailed Description
Impaired social functioning is a frequent and disabling sequela of trauma-related disorders. PTSD is associated with a high rate of severe impairment in quality of life relative to other anxiety disor...
Eligibility Criteria
Inclusion
- Phase 1:
- Age 18-45
- Self-reported healthy volunteer status
Exclusion
- Inability to provide written informed consent in English
- Inability to see task due to visual impairment
- Participants who produce T-scores of 65 or higher on any Brief Symptom Inventory (BSI) subscales will not be eligible to remain in the Trust Task participant pool.
- Phase 2:
- Inclusion Criteria:
- Female
- Trauma exposure appropriate to group
- For trauma-exposed groups the index trauma is actual or threatened physical assault or sexual violence
- PCL-5 score 33 and above (for PS-SA and PS-nonSA groups)
- Right handedness
- Age 18-45
- English as a first language
Key Trial Info
Start Date :
November 14 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 31 2022
Estimated Enrollment :
168 Patients enrolled
Trial Details
Trial ID
NCT03383536
Start Date
November 14 2017
End Date
August 31 2022
Last Update
August 31 2022
Active Locations (1)
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1
McLean Hospital
Belmont, Massachusetts, United States, 02478