Status:

COMPLETED

HRV-B for Symptom Management in Sickle Cell Patients

Lead Sponsor:

Prisma Health-Upstate

Collaborating Sponsors:

University of South Carolina

Conditions:

Sickle Cell Disease

Eligibility:

All Genders

10+ years

Phase:

NA

Brief Summary

This study will test the hypothesis that Heart Rate Variability Biofeedback (HRV-B) restores autonomic balance and reduces pain and other symptoms among patients with sickle cell disease (SCD).The spe...

Detailed Description

The purpose of this study is to see if Heart Rate Variability Biofeedback (HRV-B) can reduce chronic pain, stress, depression, anxiety, insomnia, loneliness, helplessness, physical limitations and pai...

Eligibility Criteria

Inclusion

  • SCD patients
  • 10 years old
  • English literate
  • Patient recruited through Greenville Health System
  • Any race or ethnicity
  • Any sex

Exclusion

  • Conditions affecting HRV (paroxysmal supraventricular tachycardia, atrial fibrillation, myocardial infarction within 12 months, unstable angina)
  • Medications that affect cardiac rhythm (angiotensin converting enzyme, calcium channel, or beta-adrenergic inhibitors)
  • Pacemaker or defibrillator
  • Heart transplant or by-pass surgery within 1 year
  • Active seizure disorder or use of antiseizure/anticonvulsant medication specifically for seizures
  • Dementia
  • Moderate or severe head injury or stroke within 6 months
  • Evidence of active substance abuse
  • An uncontrolled major psychiatric disorder
  • Cognitive disability that precludes participation
  • Use of long acting (extended release) opioid medications; however, 'as needed' short acting opioid medication usage is allowable

Key Trial Info

Start Date :

January 22 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 28 2018

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT03383913

Start Date

January 22 2018

End Date

December 28 2018

Last Update

October 28 2024

Active Locations (1)

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1

Center for Integrative Oncology and Survivorship

Greenville, South Carolina, United States, 29605