Status:
RECRUITING
In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells
Lead Sponsor:
Mayo Clinic
Conditions:
Healthy
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
This pilot study will first establish the feasibility of an in vivo methodology of assessing the utilization of glutamine into the TCA cycle of normal bone marrow plasma cells from healthy subjects wh...
Detailed Description
Twenty healthy adult study participants between the ages of 18 and 60 years will be recruited to participate in this pilot study that will include two groups: a) Ex Vivo group (10 volunteers) and b) I...
Eligibility Criteria
Inclusion
- Ages 18-60
- Able to provide written consent
Exclusion
- Renal Failure
- Pregnancy
- Active steroid use
- Active liver Disease
- Anemia (Hemoglobin \< 12.5 g/dL in men and \< 11.5 g/dL in women)
- H/O alcohol use (average \> 2 drinks per day)
- BMI \> 30
Key Trial Info
Start Date :
September 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2026
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT03384108
Start Date
September 1 2017
End Date
January 1 2026
Last Update
April 20 2025
Active Locations (1)
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1
Mayo Clinic
Rochester, Minnesota, United States, 55905