Status:
COMPLETED
Carbon Monoxide Headache Triggering Properties as Well as Effects on the Brain's Vessels and Blood Flow
Lead Sponsor:
Danish Headache Center
Conditions:
Headache Disorders
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
Studying Carbon monoxide effects on brain vessels in healthy volunteers with magnetic resonance imaging.
Detailed Description
In this study we will systematically investigate the headache-releasing properties of carbon monoxide as well as measure the effect of carbon monoxide on mean blood flow rate in the brain's large vess...
Eligibility Criteria
Inclusion
- Healthy volunteers
- Aged 18-50
- 50-100 kg
Exclusion
- Tension type headache more than 5 dage /month
- Other primary headaches
- Daily medication except contraceptives
- Drug taken within 4 times the halflife for the specific drug except contraceptives
- Pregnant or lactating women
- Exposure to radiation within the last year
- Headache within the last 24 hours before start of trial
- Hypertension
- Hypotension
- Respiratory or cardiac disease
- Smoking
- Primary relatives with current or previous migraine
Key Trial Info
Start Date :
October 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 12 2018
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT03385174
Start Date
October 1 2017
End Date
March 12 2018
Last Update
March 13 2018
Active Locations (1)
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1
Danish Headache Center
Glostrup Municipality, Denmark, 2600