Status:
TERMINATED
Prophylactic Antibiotics Prior to Embryo Transfer (PAPET): RCT
Lead Sponsor:
Washington University School of Medicine
Conditions:
Assisted Reproductive Technology
Antibiotic Prophylaxis
Eligibility:
All Genders
18-43 years
Phase:
NA
Brief Summary
The objective of this study is to determine the impact on clinical pregnancy rate of withholding routine prophylactic antibiotic therapy during IVF. The hypothesis is that withholding antibiotic proph...
Detailed Description
Over 200,000 in vitro fertilization (IVF) cycles were initiated in the United States in 2015,1 allowing thousands of infertile couples to start families. Although most of the steps in IVF protocols ar...
Eligibility Criteria
Inclusion
- The female partner must be aged 18-43 years and going through a fresh IVF cycle
Exclusion
- Couples will be excluded from enrollment if they have any contraindication to antibiotic treatment, are not intending to undergo embryo transfer (fertility preservation patients and oocyte donors), require use of extended antibiotic coverage at time of egg retrieval, are already on antibiotics for any reason (e.g., upper respiratory infection), have a recent history of pelvic infection, or are planning on limited insemination (inseminating a limited number of the eggs retrieved) or are using donor sperm.
Key Trial Info
Start Date :
January 21 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 31 2019
Estimated Enrollment :
96 Patients enrolled
Trial Details
Trial ID
NCT03386227
Start Date
January 21 2018
End Date
July 31 2019
Last Update
August 18 2020
Active Locations (1)
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1
Washington University Reproductive Endocrinology
St Louis, Missouri, United States, 63108