Status:
COMPLETED
Pertussis Immunization Programs in Low Income Countries - Ivory Coast
Lead Sponsor:
Institut Pasteur
Collaborating Sponsors:
Institut Pasteur of Cote d'Ivoire
Sanofi Pasteur, a Sanofi Company
Conditions:
Bordetella Pertussis, Whooping Cough
Eligibility:
All Genders
Brief Summary
Due to waning of infectious as well as vaccine immunity and lack of vaccination boosters, a large number of adolescents and adults are no longer immunized against Bordetella pertussis, the agent of wh...
Detailed Description
Background: Vaccination of infants and young children with a whole-cell pertussis (wP) vaccine dramatically decreased the mortality and morbidity due to B. pertussis. However, twenty-five years of "h...
Eligibility Criteria
Inclusion
- Inclusion Criteria (Cohort 1):
- Infants under 6 months old
- Presenting clinical signs of a whooping cough syndrome
- Written consent obtained from a parent/guardian of the child
- Inclusion Criteria (Cohort 2):
- People in regular and prolonged contact (\>3h per day) with the index case for at least 15 days before the signs of whooping cough occurred in the infected child, living (or not) in the same household.
- For the adults, written consent obtained.
- For minors under 7 yo: written consent obtained from a parent/guardian.
- For minors over 7 yo: written consent obtained from parent/guardian and oral assent obtained from the child.
- Inclusion Criteria (Cohort 3):
- Child aged between 3 and 15 yo
- Up to date first pertussis vaccination (vaccination booklet or official register)
- Last pertussis vaccination done more than one year before inclusion
- For minors under 7 yo: written consent obtained from parent/guardian.
- For minors over 7 yo: written consent obtained from parent/guardian and oral assent obtained from the child.
- Exclusion Criteria (Cohort 3):
- Pertussis vaccination done more than one year before inclusion
Exclusion
Key Trial Info
Start Date :
April 11 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 21 2021
Estimated Enrollment :
789 Patients enrolled
Trial Details
Trial ID
NCT03388034
Start Date
April 11 2019
End Date
July 21 2021
Last Update
April 1 2022
Active Locations (5)
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1
Centre de Santé Urbain à base Communautaire (CSU-Com) d'Angré
Abidjan, Côte d’Ivoire
2
CHU d'Angré
Abidjan, Côte d’Ivoire
3
Hôpital Général de Port-Bouët
Abidjan, Côte d’Ivoire
4
Hôpital Général de Yopougon Attié
Abidjan, Côte d’Ivoire