Status:

COMPLETED

Impact of Gonadotrophin REceptor Polimorphisms on the Relationship Between Serum AMH and Ovarian Response

Lead Sponsor:

Instituto Valenciano de Infertilidad, IVI VALENCIA

Conditions:

antimüllerian Hormone and Gonadotrophin Receptor Polymorphism as Predictors of Ovarian Response

Eligibility:

FEMALE

18-45 years

Brief Summary

Aim of study: To compare the relationship between serum AMH and ovarian response for IVF with the GnRH antagonist protocol in patients who are carriers of FSH and/or LH receptor polymorphisms with tho...

Detailed Description

Serum AMH has shown to have a high predictive capability of the ovarian response to stimulation for IVF. On the other hand, patients who are carriers of polymorphisms in the FSH and LH receptors, have...

Eligibility Criteria

Inclusion

  • 18-45 years of age presenting to IVF clinic
  • BMI of 18-35 kg/m2
  • Having been tested for serum AMH with the Elecsys assay
  • Being planned to undergo ovarian stimulation cycle for IVF with the GnRH antagonist protocol
  • Signed written informed consent or waiver

Exclusion

  • Current or past disease affecting ovaries, gonadotropin or sex steroid
  • Current hormone therapy

Key Trial Info

Start Date :

January 11 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 18 2019

Estimated Enrollment :

296 Patients enrolled

Trial Details

Trial ID

NCT03388099

Start Date

January 11 2018

End Date

December 18 2019

Last Update

December 20 2019

Active Locations (1)

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Valencian Institute of Infertility, IVI RMA. Valencia

Valencia, Spain, 46015