Status:

COMPLETED

Non-invasive Neurally Adjusted Ventilatory Assist Versus Nasal Intermittent Positive Pressure Ventilation for Preterm Infants After Extubation

Lead Sponsor:

King Fahad Armed Forces Hospital

Conditions:

Prematurity

Respiratory Failure

Eligibility:

All Genders

Up to 2 years

Phase:

NA

Brief Summary

Non-invasive respiratory support has been emerging in the management of respiratory distress syndrome (RDS) in preterm infants to minimise the risk of lung injury. Intermittent positive pressure venti...

Detailed Description

Study Design: Randomised controlled trial Study Setting: single center NICU level III, KFAFH tertiary care center , Jeddah Saudi Arabia

Eligibility Criteria

Inclusion

  • Born less than 32 weeks gestation with respiratory distress syndrome (RDS) and requiring endotracheal tube and mechanical ventilation.
  • Less than two weeks old
  • First extubation attempt
  • CRIB score 0-5
  • Written-informed parental consent for the study

Exclusion

  • Major congenital malformations or respiratory abnormalities
  • Neuromuscular disease
  • phrenic nerve palsy
  • Intraventricular hemorrhage (IVH) grade III or IV
  • Absence of informed consent
  • Out born infants

Key Trial Info

Start Date :

May 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 30 2019

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT03388437

Start Date

May 1 2017

End Date

April 30 2019

Last Update

July 27 2021

Active Locations (1)

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King Fahad Armed Forces Hospital

Jeddah, Saudi Arabia, 21159