Status:
COMPLETED
Single Dose Omeprazole Versus High Dose in High-risk Critically Ill Patients.
Lead Sponsor:
Menoufia University
Conditions:
Critical Illness
Eligibility:
All Genders
21-70 years
Phase:
NA
Brief Summary
Upper gastrointestinal (GIT) bleeding is common in high risk critically ill patients. Hyperacidity has been identified as one of the main reasons for bleeding.1 2 Antacids with different treatment mod...
Detailed Description
A hundred and ten high risk critically ill patients were divided into two groups, fify five patients each. Group A received intravenous (IV) omeprazole 40mg bolus dose once daily followed by normal sa...
Eligibility Criteria
Inclusion
- Mechanically ventilated patients were identified as high risk patients. Patients with nasogastric tube inserted as part of their medical care were included in the study.
Exclusion
- Patients admitted because of upper gastrointestinal bleeding, patients who were not scheduled for early enteral nutrition during the first 24 hours of intensive care unit (ICU) admission, patients with bleeding disorders, renal replacement therapy, history of gastric ulcer, gastric surgery, and the use of gastric antacids before ICU admission.
Key Trial Info
Start Date :
May 11 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 17 2017
Estimated Enrollment :
110 Patients enrolled
Trial Details
Trial ID
NCT03388463
Start Date
May 11 2016
End Date
September 17 2017
Last Update
January 3 2018
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