Status:

COMPLETED

Developing Advanced Blood-Brain Barrier Permeability Imaging for Early AD

Lead Sponsor:

NYU Langone Health

Conditions:

Alzheimer Disease

Eligibility:

All Genders

20-85 years

Brief Summary

Aging is the primary risk factor in aging-related dementia. An important initiating factor for the development and progression of cognitive impairment is disruption of the blood-brain barrier (BBB). B...

Eligibility Criteria

Inclusion

  • Subjects that have been diagnosed with aMCI ages 65-85

Exclusion

  • Pregnant, planning to get pregnant, or nursing.
  • Claustrophobia
  • Cardiac pacemaker
  • Intracranial clips, metal implants, unremovable jewelries, metal in eyes.
  • History or presence of any other major medical, neurologic or psychiatric conditions, such as Alzheimer's diseases, Parkinson's diseases, and stroke.
  • Renal or liver disease as this may cause concerns related to Gad-based contrast agent
  • Allergy to the contrast agent Gadolinium

Key Trial Info

Start Date :

December 18 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 11 2023

Estimated Enrollment :

27 Patients enrolled

Trial Details

Trial ID

NCT03389698

Start Date

December 18 2018

End Date

July 11 2023

Last Update

January 30 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

New York University School of Medicine

New York, New York, United States, 10016

Developing Advanced Blood-Brain Barrier Permeability Imaging for Early AD | DecenTrialz