Status:

COMPLETED

Possible Links Between Inflammation and Lipid Metabolism

Lead Sponsor:

Barmherzige Brüder Linz

Conditions:

Sepsis

Inflammation

Eligibility:

MALE

18-40 years

Phase:

NA

Brief Summary

It has been recognized lately that sepsis and inflammation has an important impact on lipid metabolism and that the extent of hypocholesterolemia may even be a marker of severity of illness. However, ...

Detailed Description

Sepsis is a severe clinical syndrome with still limited means of therapy and often poor prognosis. It has been recognized lately that sepsis and inflammation has an important impact on lipid metabolis...

Eligibility Criteria

Inclusion

  • Men aged 18 to 40 years
  • Written informed consent
  • No disease history
  • non-smoker
  • BNP level within the normal range
  • Normal renal function (serum creatinine of 1.3 mg/dL and/or creatinine clearance greater than 80ml/min)

Exclusion

  • Systolic blood pressure \< 90 mmHg
  • Subjects on any medication
  • History of anaphylaxis
  • Probands who suffer from infectious disease

Key Trial Info

Start Date :

December 20 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 30 2018

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT03392701

Start Date

December 20 2017

End Date

September 30 2018

Last Update

October 17 2018

Active Locations (1)

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Barmherzige Brüder Linz - Innere Medizin

Linz, Austria, 4021