Status:
COMPLETED
Effects of Transcranial Direct Current Stimulation on Reward Learning in Subclinical Depression.
Lead Sponsor:
University of Oxford
Collaborating Sponsors:
Medical Research Council
Conditions:
Dysphoria
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
This project will test whether transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) can alter reward learning behaviour in subclinical depression. tDCS is a n...
Detailed Description
The development of non-invasive brain stimulation techniques offers new approaches for the treatment of depression. TMS is an approved treatment for treatment-resistant depression in the UK and USA. t...
Eligibility Criteria
Inclusion
- Participant is willing and able to give informed consent for participation in the study
- Participant has a score of \>9 on Beck's Depression Inventory II (BDI-II)
- Fluent English-speaking
- Right-handed
Exclusion
- Currently taking psychoactive medications
- Personal or family history of epileptic fits or seizures
- Family history of extreme mood fluctuations or bipolar disorder
- Currently pregnant or current likelihood of becoming pregnant
- Significant suicidal ideation or depression requiring immediate clinical referral
Key Trial Info
Start Date :
February 2 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2021
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT03393312
Start Date
February 2 2018
End Date
December 1 2021
Last Update
November 22 2024
Active Locations (1)
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1
FMRIB Centre, John Radcliffe Hospital, University of Oxford
Oxford, United Kingdom, OX3 9DU