Status:

UNKNOWN

Comparison of the Effect of Intravenous and Perineural Dexmedetomidine in Gastric Cancer Surgery

Lead Sponsor:

Kaohsiung Medical University Chung-Ho Memorial Hospital

Conditions:

Gastric Cancer

Pain, Postoperative

Eligibility:

All Genders

20-75 years

Phase:

NA

Brief Summary

Using random case assignment to investigate the analgesic and sedative effect of intravenous dexmedetomidine and dexmedetomidine as a local anesthetic adjuvant in ultrasound-guided subcostal TAP block...

Detailed Description

The process of the experiment (brief describe) The participant patients will be randomly allocated into three groups: the intravenous dexmedetomidine group (Dex\_iv group), dexmedetomidine adding to l...

Eligibility Criteria

Inclusion

  • gastric cancer patients undergoing gastrectomy or partial gastrectomy, who receive ultrasound-guided subcostal TAP block and PCA for postoperative analgesia

Exclusion

  • surgery involved other visceral organ (eg. combined splenectomy or partial hepatectomy), patients with histories of adverse drug reaction to dexmedetomidine, bradycardia (baseline heart rate \<60 beats/min), any type of atrioventricular block in electrocardiogram (EKG), heart failure, significant renal or hepatic impairment, severe bronchopulmonary disease, any coagulant disorder, and pregnant or breast-feeding woman.

Key Trial Info

Start Date :

December 23 2017

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2020

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT03393403

Start Date

December 23 2017

End Date

December 31 2020

Last Update

January 12 2018

Active Locations (1)

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Kaohsiung Medical University Hospital

Kaohsiung City, Taiwan