Status:
COMPLETED
Effect of Terlipressin on Cerebral Oxygen Saturation During Liver Transplantation
Lead Sponsor:
Kasr El Aini Hospital
Conditions:
Terlipressin Adverse Reaction
Liver Transplantation
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
in our study the investigators aim to assess the effect of terlipressin on cerebral oxygenation monitored by cerebral oxymetry and cerebral blood flow measured by transcranial doppler.
Detailed Description
All patients will receive 6ml /kg/h Ringer acetate solution as a maintenance intraoperative fluid. If pulse pressure variations (PPV) is more than 15%, the patient will be considered as fluid responde...
Eligibility Criteria
Inclusion
- ASA II-IV undergoing orthotopic liver transplantation.
- Age above 18 years.
Exclusion
- Age below 18 years.
- Patients on Terlipressin preoperative.
- Patients known allergic to Terlipressin.
- Portal vein thrombosis.
- Ischemic heart disease.
- Patients with T. bilirubin level above 7 mg/dl
Key Trial Info
Start Date :
January 25 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 25 2018
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03395574
Start Date
January 25 2018
End Date
November 25 2018
Last Update
December 24 2018
Active Locations (1)
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1
Kasr Alainy Hospital , Faculty of Medicine
Cairo, Egypt