Status:
COMPLETED
Effects of Intensive Low-Salt Diet Education by Mobile Application on Albuminuria
Lead Sponsor:
Yonsei University
Conditions:
Albuminuria
Eligibility:
All Genders
19-65 years
Phase:
NA
Brief Summary
Albuminuria is a known risk factor for cardiovascular disease (CVD), chronic kidney disease (CKD) progression, all cause mortality. Inhibition of the renin-angiotension-aldosterone system (RAAS) plays...
Detailed Description
This is an pen-label, case-control, randomized clinical trial. * Run-in period (8 weeks) : before 8 weeks of study initiation, all of the patients have to stop all RAAS blockers or diuretics and swit...
Eligibility Criteria
Inclusion
- Age : 19-65
- Underlying hypertension or antihypertensive medication , or Systolic blood pressure ≧ 140 mmHg or Diastolic blood pressure ≧ 90
- Modification of Diet in Renal Disease study (MDRD) eGFR ≧ 30 ml/min per 1.73m2
- Random urine albumin-to-creatinine ratio ≧ 30 mg/g
- Smartphone ownership
Exclusion
- Age under 18 or over 66
- Uncontrolled hypertension (BP\>160/110 mmHg)
- Pregnancy within 6 months
- Serum potasium \> 5.5 mEq/L
- malignancy
- a diagnosis of CVD (cerebral infarction, hemorrhagic infarction, acute myocardial infarction or unstable angina, coronary angioplasty, or coronary artery bypass surgery) within the last 6 months
- Contraindication to angiotensin II receptor blocker
- life expectancy less than 6 months
Key Trial Info
Start Date :
May 10 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 12 2020
Estimated Enrollment :
108 Patients enrolled
Trial Details
Trial ID
NCT03396328
Start Date
May 10 2018
End Date
May 12 2020
Last Update
September 29 2020
Active Locations (1)
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1
Division of Nephrology, Department of Internal Medicine Yonsei University College of Medicine
Seoul, South Korea, 03722