Status:
UNKNOWN
Fecal Microbiota Transplantation and Analysis of Fecal Microbiome in IBD Patients
Lead Sponsor:
Yonsei University
Conditions:
Inflammatory Bowel Diseases
Eligibility:
All Genders
7-80 years
Phase:
NA
Brief Summary
Fecal microbiome of donor and recipient will be analyzed before and after fecal microbiota transplantation in IBD patients.
Detailed Description
Fecal microbiota transplantation will be performed to the IBD patients, and microbial analysis will be done for donor and recipient feces. Fecal microbiota transplantation will be done twice via colon...
Eligibility Criteria
Inclusion
- 7 years old to 80 years old at start of trial
- Inflammatory bowel disease such as ulcerative colitis, Crohn's disease, and Behcet's colitis
- Patients who do not respond to the conventional treatments or who do not wish/not able to use one.
- Patients who agree to participate in the trial after thorough explanation
- Evidence of active disease
Exclusion
- Patients whose CRP\<8, calprotectin\<200, and mucosal healing endoscopically (who are in stable state)
- Patients whose symptom is due to other disease than IBD
- \_Patients with immunosuppressive disease
- Patients who are clinically unstable such as massive hemorrhage or perforation
- Patients with toxic megacolon, paralytic ileus, or symptomatic intestinal obstruction
- Absolute neutrophil count (ANC) \<1.5 \*10\^9/L (1500/mm3)
- Pregnant or under breast feeding
- Patients enrolled in other clinical trials
Key Trial Info
Start Date :
November 15 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2023
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03399188
Start Date
November 15 2017
End Date
December 31 2023
Last Update
January 16 2019
Active Locations (1)
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1
Severance hospital
Seoul, South Korea, 03722