Status:

RECRUITING

Wearable MCI to Reduce Muscle Co-activation in Acute and Chronic Stroke

Lead Sponsor:

Northwestern University

Collaborating Sponsors:

Shirley Ryan AbilityLab

National Institutes of Health (NIH)

Conditions:

Stroke

Stroke, Acute

Eligibility:

All Genders

21+ years

Phase:

NA

Brief Summary

The purpose of the study is to explore the feasibility of using a wearable device, called a myoelectric-computer interface (MCI), to improve arm movement in people who have had a stroke. Impaired arm...

Eligibility Criteria

Inclusion

  • Chronic stroke participants
  • Hemiparesis from first ever stroke at least 6 months prior to screening
  • Severe motor impairment (FMA of 7-30)
  • At least some voluntary shoulder and elbow muscle activation.
  • Acute stroke participants
  • Hemiparesis from first ever stroke within the past 21 days
  • Severe motor impairment (FMA of 3-20), or total Manual Motor Score of 1-8 combined in Shoulder Abduction and Finger Extensors

Exclusion

  • Cognitive impairment with at least moderately impaired attention, or unable to follow instructions of the MCI task
  • Visual impairment (such as hemianopia) preventing full view of the screen
  • Anesthesia or neglect in the affected arm, or visual hemineglect (score of 2 on the NIH Stroke Scale Extinction and Inattention subtest).
  • Participation in another study on the affected arm within 6 weeks of enrollment or any pharmacological study
  • Inability to understand or follow commands in English due to aphasia or other reason
  • Diffuse or multifocal infarcts
  • Substantial arm pain preventing participation for 90 minutes a day
  • New spasticity treatment (pharmacological or Botox)

Key Trial Info

Start Date :

January 15 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

96 Patients enrolled

Trial Details

Trial ID

NCT03401762

Start Date

January 15 2018

End Date

December 1 2025

Last Update

November 25 2024

Active Locations (1)

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1

Northwestern University

Chicago, Illinois, United States, 60611