Status:

UNKNOWN

Defining the Molecular Risk in Israeli Patients With Secondary Compared to Primary Myelofibrosis

Lead Sponsor:

Assaf-Harofeh Medical Center

Conditions:

Myelofibrosis, Primary

Myelofibrosis, Post PV

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The aim of the study is to determine the rate of HMR mutations in PMF and secondary MF (post PV/ET) subjects, and correlate the rate of mutations with clinical features as known prognostic scores.

Detailed Description

Main inclusion criteria: 1. Diagnosis of PMF, post PV MF or post ET MF according to the WHO 2008 classification 2. Age ≥ 18 years 3. Concurrent participation in clinical trials will be allowed. Effi...

Eligibility Criteria

Inclusion

  • Diagnosis of PMF, post PV MF or post ET MF according to the WHO 2008 classification
  • Age . 18 years
  • Patient is willing and capable of giving a written informed consent.
  • Concurrent participation in clinical trials will be allowed

Exclusion

  • Unwilling or unable to provide informed consent
  • Prefibrotic MF

Key Trial Info

Start Date :

December 10 2017

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 9 2020

Estimated Enrollment :

222 Patients enrolled

Trial Details

Trial ID

NCT03402399

Start Date

December 10 2017

End Date

December 9 2020

Last Update

July 5 2019

Active Locations (1)

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Assaf Harofeh Medical Center

Ẕerifin, Israel