Status:
COMPLETED
Metabolomics of the Dietary Approaches to Stop Hypertension (DASH) Dietary Pattern
Lead Sponsor:
Johns Hopkins Bloomberg School of Public Health
Collaborating Sponsors:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Dietary Modification
Blood Pressure
Eligibility:
All Genders
22-100 years
Brief Summary
The present record represents a secondary data analysis of the Dietary Approaches to Stop Hypertension (DASH) trial. Study data and specimens were accessed through the National Heart, Lung, and Blood ...
Detailed Description
The present study was conducted in order to: 1) quantify the metabolomic expression of the DASH dietary pattern; and 2) examine the relationship between metabolites that reflect the DASH dietary patte...
Eligibility Criteria
Inclusion
- Men and women with systolic blood pressure \<160 mmHg and diastolic blood pressure 80-95 mmHg
Exclusion
- Taking anti-hypertensive medication
- Poorly controlled diabetes mellitus
- Hyperlipidemia
- Cardiovascular event within the past 6 months
- Chronic disease that may interfere with participation
- Pregnancy or lactation
- Body mass index \> 35 kg/m2
- Unwilling to stop taking vitamin or mineral supplements or antacids
- Kidney disease
- Consumption of \>14 alcoholic beverages per week
- Did not consent to the use of biological specimens
- Did not attend the 8 week follow-up visit
- No serum specimen or insufficient volume of serum specimens in repository
Key Trial Info
Start Date :
August 1 1993
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2017
Estimated Enrollment :
459 Patients enrolled
Trial Details
Trial ID
NCT03403166
Start Date
August 1 1993
End Date
June 1 2017
Last Update
January 18 2018
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