Status:
TERMINATED
Dual-Energy CT on Plan Quality, Dose-delivery Accuracy, and Simulated Outcomes of Patients Treated With Proton or Photon Therapy
Lead Sponsor:
Washington University School of Medicine
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Lung Cancer
Brain Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The aim of this protocol is to refine the accuracy of proton beam therapy (PT) by the use of dual energy computed tomography (DECT), in conjunction with novel iterative image reconstruction algorithms...
Eligibility Criteria
Inclusion
- Eligibility Criteria:
- Diagnosis of histologically proven primary or metastatic cancer requiring thoracic radiation therapy OR radiation therapy to the head and neck or brain
- At least 18 years of age.
- Planning to undergo proton or photon beam radiation therapy as part of the clinical management of the diagnosed cancer.
- Able to understand and willing to sign an IRB-approved written informed consent document.
Exclusion
- Implanted metallic objects in the region to be scanned excepting dental prostheses
- IV or oral contrast medium within 24 hours prior to DECT image acqusition
- Pregnant.
Key Trial Info
Start Date :
June 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 11 2022
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT03403361
Start Date
June 1 2018
End Date
August 11 2022
Last Update
March 1 2024
Active Locations (1)
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1
Washington University School of Medicine
St Louis, Missouri, United States, 63110