Status:

TERMINATED

Evaluating the Feasibility of a Stepped-care Approach to Treating Adolescents With Binge and Loss of Control Eating

Lead Sponsor:

Virginia Commonwealth University

Conditions:

Overweight and Obesity

Pediatric Obesity

Eligibility:

All Genders

13-18 years

Phase:

NA

Brief Summary

There are limited evidence-based treatments for adolescents with binge eating and fewer specifically targeting adolescents with both binge eating and overweight/obesity. The existing research for adol...

Detailed Description

Binge eating affects a significant number of adolescents. Among adolescents seeking obesity treatment, rates of binge eating behavior range from 20-36%. Studies of non-treatment seeking adolescents ha...

Eligibility Criteria

Inclusion

  • Adolescent
  • Overweight (BMI ≥85% percentile for age and gender according to the CDC Growth Charts)
  • Males and females ages 13 to 18 years
  • Must endorse loss of control (LOC) eating
  • Adolescent must reside with the primary participating caregiver who is also willing to participate in the study
  • Caregiver
  • Participating caregiver must be at least 18 years of age
  • Participating caregiver must reside with the adolescent
  • Participating caregiver must be willing to participate in the standard intervention
  • Participating caregiver may be another relative (i.e., grandparents) or legal guardian as long as he/she resides with the adolescent and has primary responsibility for the child.
  • Adolescent

Exclusion

  • Non-English speaking
  • Medical condition(s) that may be associated with unintentional weight change (e.g., hypothalamic injury, Prader Willi, or malignancy)
  • Uncontrolled diabetes mellitus diagnosed by history or a fasting glucose ≥126 mg/dl (subjects with glucose intolerance or "prediabetes" will be eligible for study participation)
  • Use of oral glucocorticoids, atypical antipsychotics, weight loss medications, diuretic medication or an investigational medication within 3 months of study participation
  • Medical condition(s) that may be negatively impacted by exercise
  • Psychiatric, cognitive, physical or developmental conditions that would impair the adolescent's ability to complete assessments, participate in a group, or conduct physical activity
  • Reports of compensatory behaviors (i.e., vomiting, laxative, abuse, excessive exercise) in the past 3 months
  • Current pregnancy or plan to become pregnant during study period
  • Previous participation in Clinical Trials #(INSERT)
  • Current participation in another weight loss program
  • Personal history of weight loss surgery
  • Weight in excess of 400 pounds
  • Admission to a psychiatric hospital within the past year.
  • In addition, adolescents will be excluded from participation (and referred for further evaluation) based on the results of baseline psychological assessments under the following circumstances: 1) clinically significant depression, evidenced RCADS or or during screening / behavioral interview; 2) active suicidality as reported on surveys or during screening / behavioral interview; 3) clinically significant eating disorder based on assessments or during screening/behavioral interview.
  • Adolescents taking metformin, oral contraceptives, tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), or stimulant medications may be eligible for participation; however, subjects must be on a stable dose of medication for at least 3 months prior to study participation.
  • Caregiver

Key Trial Info

Start Date :

February 15 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 7 2018

Estimated Enrollment :

4 Patients enrolled

Trial Details

Trial ID

NCT03404713

Start Date

February 15 2018

End Date

November 7 2018

Last Update

October 15 2024

Active Locations (1)

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1

Virginia Commonwealth University

Richmond, Virginia, United States, 23298