Status:
COMPLETED
MR-guided RAdiotherapy to Breast With Dose Escalation to regionaL Lymph NodEs
Lead Sponsor:
Royal Marsden NHS Foundation Trust
Conditions:
Breast Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Radiotherapy to the breast and lymph nodes is routinely planned using CT scans. The introduction of magnetic resonance imaging (MRI) has the potential to better visualise the lymph nodes and so define...
Detailed Description
MR imaging has the potential to improve both the localisation of pan-LN treatments and the subsequent treatment delivery using MR-linac technology. The MIRABELLE study will apply the MR sequences deve...
Eligibility Criteria
Inclusion
- Age ≥18 years
- Female or male
- Invasive carcinoma of the breast (left or right-sided)
- cT1-T4,N3,M0-1 disease
- Due to proceed to primary treatment (chemo, surgery, radiotherapy and/or endocrine therapy)
- Histopathological involvement of axillary lymph nodes confirmed on FNA or Bx
- Likely to undergo locoregional radiotherapy as part of their breast cancer management
Exclusion
- Implanted pacemakers and/or pacing wires
- Cochlear implants
- Programmable hydrocephalus shunts
- Implanted neurostimulation systems
- Implanted drug infusion pumps
- Ferromagnetic implants
- Claustrophobia
Key Trial Info
Start Date :
December 18 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 12 2019
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT03405519
Start Date
December 18 2017
End Date
December 12 2019
Last Update
August 17 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
The Royal Marsden NHS Foundation Trust
Sutton, Surrey, United Kingdom, SM2 5PT