Status:
COMPLETED
Zinc-MNP Trial for Prevention of Diarrhea and Promotion of Linear Growth
Lead Sponsor:
UCSF Benioff Children's Hospital Oakland
Collaborating Sponsors:
International Centre for Diarrhoeal Disease Research, Bangladesh
Johns Hopkins Bloomberg School of Public Health
Conditions:
Diarrhea
Stunting
Eligibility:
All Genders
9-11 years
Phase:
NA
Brief Summary
This is a randomized, double-blind, community-based efficacy trial of different doses, forms, and frequencies of zinc supplementation for the prevention of diarrhea and promotion of linear growth amon...
Detailed Description
Zinc is essential to support growth in young children especially for tissues undergoing rapid cellular differentiation and turnover, such as those in the immune system and gastrointestinal tract. Ther...
Eligibility Criteria
Inclusion
- 9-11 months of age
- Weight-for-length Z score \>= -3 according to the 2006 World Health Organization Growth Standards
- Hemoglobin concentration \> = 7.0 g/dL
Exclusion
- Presence of severe acute malnutrition, defined as a WLZ \<-3 and/or the presence of bipedal edema and/or mid-upper arm circumference \<115 mm;
- Presence of severe anemia, defined as a hemoglobin concentration \< 7.0 g/dL
- Congenital anomalies (e.g. cardiac defects, cleft lip or palate) or any other conditions that interfere with feeding;
- Chromosomal anomalies and other organic problems (e.g. jaundice, tuberculosis)
- Currently consuming MNPs with no intention of stopping
Key Trial Info
Start Date :
February 20 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 12 2020
Estimated Enrollment :
2886 Patients enrolled
Trial Details
Trial ID
NCT03406793
Start Date
February 20 2018
End Date
January 12 2020
Last Update
November 3 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Icddr,B
Dhaka, Bangladesh