Status:

COMPLETED

PRimary Care Opioid Use Disorders Treatment (PROUD) Trial

Lead Sponsor:

Kaiser Permanente

Collaborating Sponsors:

National Institute on Drug Abuse (NIDA)

The Emmes Company, LLC

Conditions:

Opioid-use Disorder

Eligibility:

All Genders

16-90 years

Phase:

NA

Brief Summary

Effective treatment for opioid use disorders (OUDs) requires medications. Two medications for treating OUDs-buprenorphine and injectable naltrexone-can be prescribed in primary care (PC). However, des...

Eligibility Criteria

Inclusion

  • The 12 clinics were eligible if their health system leaders agreed they would participate prior to study start.
  • Patients are eligible for inclusion in the sample for analyses of the PROUD trial if they visited one of the randomized clinics at any time in the 5 year study period. Specific inclusion criteria for the trial are:
  • Age is 16 to 90 years at any time during the study; and
  • Visited a PROUD trial primary care clinic in the 3 years prior to randomization or the 2 years after (note: one of the 6 study sites may only be able to provide EHR data for 2 years before randomization)

Exclusion

  • Patients who have requested through their health systems to opt out of research will be excluded from this study.

Key Trial Info

Start Date :

February 28 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 29 2020

Estimated Enrollment :

973759 Patients enrolled

Trial Details

Trial ID

NCT03407638

Start Date

February 28 2018

End Date

February 29 2020

Last Update

May 18 2025

Active Locations (6)

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Page 1 of 2 (6 locations)

1

University of Miami Health System

Miami, Florida, United States, 33136

2

Henry Ford Health System

Detroit, Michigan, United States, 48202

3

Montefiore Medical Center

The Bronx, New York, United States, 10467

4

Harris Health System

Houston, Texas, United States, 77054