Status:
COMPLETED
A Study to Assess the Carriage of Pneumococci in Children Aged ≤8 Years, and Their Household Contacts
Lead Sponsor:
Public Health England
Conditions:
Immunization; Infection
Eligibility:
All Genders
Brief Summary
Since the introduction of pneumococcal conjugate vaccines, this research group has conducted several carriage studies. These were at key points in the evolution of the pneumococcal immunisation schedu...
Detailed Description
Streptococcus pneumoniae frequently colonises the human nasopharynx and most carriers remain asymptomatic. However, sometimes the organism may spread locally to cause non-invasive, mucosal infections ...
Eligibility Criteria
Inclusion
- At least one child aged ≤8 years in the household
- Written informed consent obtained from the child's parent / legal guardian for their participation, and for any participating household contacts
Exclusion
- Moderate to severe cerebral palsy or other debilitating condition
- Syndromes and neurological disorders affecting swallowing.
- Ear, nose \& throat disorders affecting local anatomy for swabbing (e.g. malformed ears)
- Confirmed or suspected immunodeficiency (congenital or acquired) or receiving immunosuppressive therapy.
Key Trial Info
Start Date :
February 14 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 31 2018
Estimated Enrollment :
280 Patients enrolled
Trial Details
Trial ID
NCT03407690
Start Date
February 14 2018
End Date
July 31 2018
Last Update
August 29 2019
Active Locations (2)
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1
Gloucestershire Primary Care
Gloucester, Gloucestershire, United Kingdom
2
Hertfordshire primary care
Hertford, Hertfordshire, United Kingdom