Status:
COMPLETED
HPA Antibodies and the Distribution of Antigen and Antibodies
Lead Sponsor:
Guangzhou First People's Hospital
Collaborating Sponsors:
LanZhou University
First Affiliated Hospital of Harbin Medical University
Conditions:
Blood Disease
Platelet Refractoriness
Eligibility:
All Genders
Phase:
NA
Brief Summary
By detecting platelet antibodies of participants and then further to identify their genotype and analyzing laboratory examination, the investigators will obtain positive frequency of HPA antibodies, t...
Detailed Description
1. The investigators will detect platelet antibodies of participants who are according with the inclusive criteria. 2. For participants with platelet antibodies, the investigators should screen out ca...
Eligibility Criteria
Inclusion
- Blood disease patients with voluntary participation in creating records, no gender limitation, 0-99 years of age, first diagnosed or be hospitalized in our hospital with platelet transfusion more than once.
- Patients transfers from other hospitals which can be confirm the time (\>1) of platelet transfusion.
- Patient be cured, discharged or dead with the time of platelet transfusion is between 1 to 10 should be included.
- Patient with HPA antibodies at admission could be considered to be included into same type transfusion group.
- \-
Exclusion
- Patients informed but refuse to participate in;
- Patients with HPA antibodies quitting therapy or breaking off cooperation during research;
- Patients with many referrals and the time of platelet transfusion can not be confirmed;
- Patient without platelet transfusion;
- Patient with termination of treatment whatever active or passive. -
Key Trial Info
Start Date :
January 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2020
Estimated Enrollment :
6170 Patients enrolled
Trial Details
Trial ID
NCT03408158
Start Date
January 1 2017
End Date
December 31 2020
Last Update
August 12 2021
Active Locations (1)
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1
Guangzhou First People's Hospital
Guangzhou, Guangdong, China, 210000