Status:
UNKNOWN
Impact of Intravenous Lidocaine During Colorectal Surgery on Pain and Immune Functions
Lead Sponsor:
Ciusss de L'Est de l'Île de Montréal
Collaborating Sponsors:
Foundation of Anesthesia and Resuscitation of Quebec
Conditions:
Intravenous Lidocaine and Immunity
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
This study evaluates the impact of intraoperative intravenous lidocaine administered during laparoscopic colorectal surgery on the intraoperative remifentanil consumption as well as postoperative pain...
Detailed Description
Hypothesis: We hypothesize that the intravenous lidocaine (IVL) versus placebo administered during laparoscopic colorectal surgery will allow for: a reduction in intraoperative remifentanil consumptio...
Eligibility Criteria
Inclusion
- ASA status I, II or III
- Patients older than 18 years
- Colonic surgery
- Classical management of ERAS program patients in our center
Exclusion
- Arrhythmia, abnormal electrocardiographic , antiarrhythmic therapy
- Immunosuppressive treatments, corticosteroids or long-term NSAIDs (multiple weekly doses) or during preoperative 48 hours
- conversion intraoperative of a laparoscopic surgical technique to a laparotomy technique
- Pregnant women
- Inability to complete the questions related to this study
- Inability to use hydromorphone postoperative PCA
- Intolerance or allergy to lidocaine, hydromorphone or any other drug that is included in the protocol for perioperative management
- Unexpected events leading to the exclusion:
- Difficult unplanned intubation
- Surgical complication requiring aggressive haemodynamic support (vasopressors, inotropes, transfusion)
Key Trial Info
Start Date :
April 29 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03410836
Start Date
April 29 2019
End Date
June 1 2025
Last Update
October 18 2023
Active Locations (1)
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1
Hôpital Maisonneuve-Rosemont, CIUSSS de l'Est de l'Ile de Montréal
Montreal, Quebec, Canada, H1T2M4