Status:
TERMINATED
Impact of Early Enteral vs. Parenteral Nutrition on Risk of Gastric-Content Aspiration in Patients Requiring Mechanical Ventilation and Catecholamines
Lead Sponsor:
Centre Hospitalier Departemental Vendee
Collaborating Sponsors:
Ministry of Health, France
Institut National de la Santé Et de la Recherche Médicale, France
Conditions:
Acute Respiratory Failure
Shock
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
To evaluate the impact of enteral nutrition on microaspiration of gastric content and pharyngeal secretions
Detailed Description
A common obstacle to enteral nutrition is gastrointestinal intolerance, with regurgitations potentially responsible for gastric-content aspiration. Several studies involving technetium 99m (99mTc) lab...
Eligibility Criteria
Inclusion
- Invasive mechanical ventilation expected to be required more than 48 hours
- Nutrition started within 24 hours after initiation of endotracheal mechanical ventilation
- Treatment with vasoactive drug administered via a central venous catheter
- Age over 18 years
- Signed information
Exclusion
- Abdominal surgery within 1 month before inclusion
- History of esophageal, gastric, duodenal or pancreatic surgery
- Bleeding from the esophagus, stomach or bowel
Key Trial Info
Start Date :
January 27 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 7 2015
Estimated Enrollment :
139 Patients enrolled
Trial Details
Trial ID
NCT03411447
Start Date
January 27 2015
End Date
July 7 2015
Last Update
January 26 2018
Active Locations (6)
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1
CHU Amiens
Amiens, France, 80054
2
Centre hospitalier d'Annecy
Annecy, France, 74374
3
CHU Louis Mourier
Colombes, France
4
CHU Lille
Lille, France, 59000