Status:
COMPLETED
Resistance Exercise and Muscle Protein Synthesis in Obese Adults
Lead Sponsor:
University of Illinois at Urbana-Champaign
Conditions:
Obesity
Eligibility:
All Genders
20-45 years
Phase:
NA
Brief Summary
Obesity has numerous comorbidities that are associated with exceedingly high healthcare costs. In addition to well- characterized impairments in lipid and glucose metabolism, obesity is associated wit...
Detailed Description
Baseline procedures: A parallel group design will be used for this study. Prior to the infusion trial, participants will reported to the laboratory on two separate occasions in the morning. On the fi...
Eligibility Criteria
Inclusion
- Inclusion criteria
- Healthy-weight adults: BMI 18-24.9 kg/m2
- Obese adults: BMI 30-39.9 kg/m2
- Aged between 20-45 years
- Healthy
- Sedentary
- Exclusion criteria
- Smoking
- Allergies to pork consumption
- Unusually high protein consumption
- Vegetarians
- Phenylketonuria (PKU)
- Diagnosed GI tract diseases
- Arthritic conditions
- A history of neuromuscular problems
- Previous participation in amino acid tracer studies
- Predisposition to hypertrophic scarring or keloid formation
- Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications).
- Irregular menstrual cycles during the previous year
- Pregnancy
- High BMI that is not representative of being obese (e.g. resistance trained individuals, football players)
- Contraindications for exercise
Exclusion
Key Trial Info
Start Date :
January 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2018
Estimated Enrollment :
19 Patients enrolled
Trial Details
Trial ID
NCT03411681
Start Date
January 1 2017
End Date
May 1 2018
Last Update
May 1 2018
Active Locations (1)
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1
Freer Hall
Urbana, Illinois, United States, 61801