Status:

COMPLETED

Endovascular Treatment of Peripheral Artery Disease (PAD)

Lead Sponsor:

Duomed

Conditions:

Peripheral Arterial Disease

Iliac Artery Disease

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this observational study is to evaluate the performance and safety of endovascular treatment with stenting (Optimed Sinus Superflex 635 or Qualimed Pontos-pp) or balloon angioplasty (Ca...

Eligibility Criteria

Inclusion

  • Patient must sign the informed consent form prior to the index-procedure.
  • Patient is older than 18 years.
  • Patient is compliant with the requested follow-up visits at week 6 and month 12 and the treatment regime.
  • Patient suffers from mild to intermittent claudication (Rutherford 1-3) or critical limb ischemia (Rutherford 4-5).
  • Target lesion is an occlusion or diameter stenosis is ≥50% by visual estimate.
  • Target lesion is located in the common and external iliac artery, in the common and superficial femoral artery, popliteal artery and/or the below-the-knee (BTK) arteries (anterior tibial artery, posterior tibial artery or peroneal artery).

Exclusion

  • Patients with Rutherford 0 and 6.
  • Patient is pregnant.
  • Patients with estimated Glomerular filtration rate (eGFR) \< 30 mL/min/1.73m2.
  • Patient has an acute thrombus or aneurysm in the target arteries.
  • Patient has a life expectancy of \<12 months.
  • Patient has a target lesion that cannot be crossed with a guidewire.
  • Patient suffers from acute limb ischemia defined as any sudden decrease in limb perfusion causing a potential threat to limb viability.
  • Patient has scheduled elective non-vascular procedures within 3 months after index-procedure. Vascular procedures are allowed within 3 months after the index-procedure if it is guaranteed that acetylic salicylic acid and clopidogrel intake is not interrupted.
  • Contraindication for anti-thrombotic therapy (coagulopathy, …).
  • Patient has a known intolerance to anti-thrombotic medication or contrast agents.

Key Trial Info

Start Date :

May 2 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2021

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT03414515

Start Date

May 2 2018

End Date

December 1 2021

Last Update

September 5 2024

Active Locations (1)

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1

Heilig Hart Ziekenhuis

Mol, Antwerp, Belgium, 2400