Status:

UNKNOWN

Comparison of Anesthetic Efficacy of Dexmedetomidine and Epinephrine With Lidocaine in Irreversible Pulpitis

Lead Sponsor:

Postgraduate Institute of Dental Sciences Rohtak

Conditions:

Irreversible Pulpitis

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

Aim of the study is to determine and compare the anaesthetic efficacy of dexmedetomidine and epinephrine in combination with 2% lidocaine for inferior nerve block in patients with irreversible pulpiti...

Detailed Description

AIMS AND OBJECTIVES: To evaluate the efficacy of conventional inferior alveolar nerve block in mandibular molars with symptomatic irreversible pulpitis with injection dexmedetomidine plus injection l...

Eligibility Criteria

Inclusion

  • 18-50 years of age.
  • Patient willing to participate in the study.
  • Mature permanent mandibular first and second molars exhibiting signs of symptomatic irreversible pulpitis as assessed by history, cold and electric pulp tests.
  • Absence of periapical lesions on radiographic examination.

Exclusion

  • Patient not ready to participate in the study voluntarily
  • Clinical history or electrocardiographic evidence of heart block, Ischaemic heart disease
  • Asthma, Sleep apnoea syndrome.
  • Impaired liver, renal or mental function.
  • Alcohol consumption in excess of 28 units per week.
  • Chronic sedative and analgesic user and those having known allergy to study drugs
  • Patients with severe periodontal disease.
  • Patients unable to return for recall appointments
  • Signs or symptoms of external /internal resorption, furcation or periapical radiolucency, swelling, or sinus tract.
  • Negative response to cold and electric pulp tests.
  • Antibiotic or analgesic intake within past 24 hours before treatment

Key Trial Info

Start Date :

February 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 30 2018

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT03415724

Start Date

February 1 2018

End Date

April 30 2018

Last Update

February 1 2018

Active Locations (1)

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Post Graduate Institute of Dental Sciences

Rohtak, Haryana, India, 124001