Status:

RECRUITING

Ethanol Gel Versus Steroid in Refractory Lumbar Discogenic Pain

Lead Sponsor:

Gelscom SAS

Collaborating Sponsors:

CEISO

Conditions:

Lumbar Discogenic Pain (Disorder)

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

DISCOGEL® is on the market since 2007. About 20,000 kits were sold to date (October 2017). The device re-obtained its CE mark in 2017. A clinical evaluation was performed by bibliographic route in 20...

Eligibility Criteria

Inclusion

  • Patient 18 years of age or older;
  • 2-month refractory pain to conservative treatment, non-surgical patients;
  • Chronic discogenic pain (1 or 2 lumbar discs) with concordant MR imaging;
  • Symptomatic for at least 8 weeks despite appropriate medical treatment;
  • Patient who agrees to participate in the study and who signed the informed consent form;
  • Patient with social protection.

Exclusion

  • Previous surgical treatment of the studied disc(s);
  • Patient with pure radicular pain;
  • Sick leave of more than 12 months secondary to the symptoms;
  • Patients who cannot read or write French;
  • History of cognitive-behavioral disorders that could interact with assessment by self-questionnaire;
  • Local or general infection, or suspicion of infection;
  • Severe coagulation disorders;
  • Other rheumatic inflammatory disease;
  • Undercurrent serious pathology with life expectancy \< 2 years;
  • Female of childbearing age that are known to be pregnant during inclusion visit or wishing to become pregnant before treatment;
  • Subject who has forfeited their freedom by administrative or legal award, or is under guardianship or under limited judicial protection
  • Patient participating in another interventional clinical trial or testing an experimental drug within 30 days of inclusion in the study.

Key Trial Info

Start Date :

May 29 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 29 2027

Estimated Enrollment :

230 Patients enrolled

Trial Details

Trial ID

NCT03415828

Start Date

May 29 2018

End Date

May 29 2027

Last Update

September 29 2025

Active Locations (5)

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Page 1 of 2 (5 locations)

1

Hospital Pellegrin

Bordeaux, France

2

Hospital St-Dié-des-Vosges

Saint-Dié, France

3

Hospital SUD La Reunion

Saint-Pierre, France

4

Hospital St-Etienne

Saint-Priest-en-Jarez, France