Status:
UNKNOWN
Intracranial Artery Stenosis Magnetic Resonance Imaging: Aetiology and Progression
Lead Sponsor:
Tsinghua University
Collaborating Sponsors:
Xuanwu Hospital, Beijing
Beijing Tiantan Hospital
Conditions:
Ischemic Stroke
Transient Ischemic Attack
Eligibility:
All Genders
18-80 years
Brief Summary
Stroke has become the leading cause of death in China. It has been shown that intracranial artery stenosis (ICAS) plays a key role in Chinese stroke patients. Although most of stenotic diseases in int...
Eligibility Criteria
Inclusion
- Patients with recent transient ischemic attack or ischemic stoke within two weeks after symptom onset and intracranial artery stenosis (30%-99%) at least in intracranial internal carotid artery,basilar artery, M1 segment of middle cerebral artery , A1 segment of anterior cerebral artery, or P1 segment of posterior cerebral artery determined by computed tomography angiography or magnetic resonance (MR) angiography.
Exclusion
- Patients with specific carotid artery atherosclerotic plaques
- Patients with evidence of may causing cardiac thrombosis disease
- Patients with claustrophobia
- Patients with contraindications to MR imaging
- Patients with heart or respiratory failure
- Patients with renal insufficiency (serum creatinine \>133umol/L)
- Patients with serious disturbance of consciousness
- Patients with brain tumors
- Patients with cerebral hemorrhage
- Pregnant woman or plan to pregnant within recent 2 years
Key Trial Info
Start Date :
October 14 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 25 2022
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT03417063
Start Date
October 14 2017
End Date
March 25 2022
Last Update
January 31 2018
Active Locations (1)
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1
Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University
Beijing, China, 100084