Status:
COMPLETED
Low Intensity Physical Activity During Sitting on Glycemic Control and Vascular Function in Obese Individuals
Lead Sponsor:
University of Missouri-Columbia
Conditions:
Obesity
Metabolic Syndrome
Eligibility:
All Genders
20-60 years
Phase:
NA
Brief Summary
Prolonged sitting is a common behavior in contemporary humans. In epidemiological studies, increased sitting time has been associated with increased risk for cardiovascular disease and all-cause morta...
Detailed Description
Experimental Design: Twenty obese subjects with metabolic syndrome will complete 2 study days with measures vascular function and glycemic control. On one study day, the subjects will sit quietly for ...
Eligibility Criteria
Inclusion
- Obese males and females with metabolic syndrome, aged 20-60 years old.
- According to the NCEP ATP III definition, metabolic syndrome is present if three or more of the following five criteria are met:
- waist circumference over 40 inches (men) or 35 inches (women),
- blood pressure over 130/85 mmHg,
- fasting triglyceride (TG) level over 150 mg/dl,
- fasting high-density lipoprotein (HDL) level less than 40 mg/dl (men) or 50 mg/dl (women)
- fasting blood sugar over 100 mg/dl.
Exclusion
- they smoke
- they have any known cardiovascular, pulmonary or metabolic disease
- have type 2 diabetes
- if good quality Doppler ultrasound image of their arteries cannot be obtained and/or evidence of plaque.
Key Trial Info
Start Date :
March 20 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2020
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT03419754
Start Date
March 20 2018
End Date
March 1 2020
Last Update
March 24 2020
Active Locations (1)
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1
University of Missouri
Columbia, Missouri, United States, 65211