Status:

UNKNOWN

Diagnostic Agreement of iFR and QFR.

Lead Sponsor:

Contilia Clinical Research Institute

Conditions:

Fractional Flow Reserve, Myocardial

Coronary Artery Disease

Eligibility:

All Genders

18+ years

Brief Summary

A Prospective, observational, single center diagnostic study to investigate the the diagnostic agreement between QFR and the pressure wire-based iFR in a real world setting.

Detailed Description

During coronary angiography, intermediate stenoses can not be adequately assessed by visual assessment alone. It is necessary to evaluate the functional significance to guide their treatment. Fractio...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Age \> 18 with symptoms of myocardial ischemia and angina or angina equivalent (chest pain, abnormal stress testing, abnormal noninvasive testing)
  • Patients witch semi recent (\>3 days) acute coronary syndromes can be included but only for the non-culprit vessels and outside of primary intervention during acute myocardial infarction.
  • Willing to participate and able to understand, read and sign the informed consent document before the planned procedure
  • Eligible for coronary angiography and/or percutaneous coronary intervention
  • Coronary artery disease with at least 1 or more visually assessed de novo coronary stenosis (30-90% diameter stenosis) in native major epicardial vessel or its branches by coronary angiogram.
  • Exclusion criteria:
  • Contraindication to adenosine administration
  • Previous Coronary Artery Bypass surgery with patent grafts to the interrogated vessel

Exclusion

    Key Trial Info

    Start Date :

    July 18 2017

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    October 1 2018

    Estimated Enrollment :

    250 Patients enrolled

    Trial Details

    Trial ID

    NCT03420131

    Start Date

    July 18 2017

    End Date

    October 1 2018

    Last Update

    February 5 2018

    Active Locations (1)

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    Contilia heart and vascular center

    Essen, North Rhine-Westphalia, Germany, 45138