Status:

UNKNOWN

Genetic Analysis of Prostate Cancer to Identify Predictive Markers of Disease Relapse or Metastatic Evolution

Lead Sponsor:

University Hospital, Lille

Collaborating Sponsors:

Weill Medical College of Cornell University

New York Presbyterian Hospital

Conditions:

Prostatic Neoplasms

Eligibility:

All Genders

18+ years

Brief Summary

Developing a genetic study on localized or locally advanced prostate cancer. The aim of the study is to identify genomic alteration predictive of metastatic recurrence in the context of primary hetero...

Eligibility Criteria

Inclusion

  • Patients managed by radical prostatectomy for prostate cancer between 2000 and 2016.
  • Follow up \> 6 years
  • Negative pre surgical extension assessment
  • Prognostic Grade Groups (OGG) III-IV-V
  • Biochemical recurrence defined by 2 consecutive PSA rises ≥ 0,2 ng/mL
  • Metastasis positive imaging

Exclusion

  • Neoadjuvant therapy
  • Follow up \< 6 years
  • Prognostic Grade Groups (PGG) I-II
  • Biochemical recurrence with metastasis negative imaging

Key Trial Info

Start Date :

May 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 1 2020

Estimated Enrollment :

84 Patients enrolled

Trial Details

Trial ID

NCT03421015

Start Date

May 1 2017

End Date

July 1 2020

Last Update

November 7 2019

Active Locations (1)

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Hôpital Claude Huriez, CHRU

Lille, France