Status:

COMPLETED

Oral Omadacycline vs. Oral Nitrofurantoin for the Treatment of Cystitis

Lead Sponsor:

Paratek Pharmaceuticals Inc

Conditions:

Uncomplicated Urinary Tract Infection

Cystitis

Eligibility:

FEMALE

18+ years

Phase:

PHASE2

Brief Summary

The purpose of this study is to evaluate the safety and efficacy of oral omadacycline as compared to oral nitrofurantoin in the treatment of female adults with cystitis.

Detailed Description

Participants were randomized to receive 7 days of treatment of either omadacycline or nitrofurantoin. The End of Treatment visit, Post Therapy Evaluation visit, and Final Follow-up visit was planned w...

Eligibility Criteria

Inclusion

  • Female participants, age 18 or older who have signed the informed consent form
  • Must have a qualifying uncomplicated urinary tract infection
  • Participants must not be pregnant at the time of enrollment
  • Must agree to a reliable method of birth control during the study and for 30 days following the last dose of study drug

Exclusion

  • Males
  • Evidence of complicated urinary tract infection (UTI), upper UTI, vaginitis, or sexually transmitted infection
  • Evidence of significant immunological disease
  • Has received an investigational drug within the past 30 days
  • Participants who are pregnant or nursing

Key Trial Info

Start Date :

January 4 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 5 2019

Estimated Enrollment :

225 Patients enrolled

Trial Details

Trial ID

NCT03425396

Start Date

January 4 2018

End Date

June 5 2019

Last Update

June 9 2020

Active Locations (23)

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Page 1 of 6 (23 locations)

1

Site 106

Chula Vista, California, United States, 91911

2

Site 101

La Mesa, California, United States, 91942

3

Site 109

Los Angeles, California, United States, 90017

4

Site 114

Aventura, Florida, United States, 33180

Oral Omadacycline vs. Oral Nitrofurantoin for the Treatment of Cystitis | DecenTrialz