Status:

UNKNOWN

Secret Micro-Needle Fractional RF System® for the Treatment of Facial Wrinkles

Lead Sponsor:

Goldman, Butterwick, Fitzpatrick and Groff

Collaborating Sponsors:

Ilooda Co., Ltd.

Conditions:

Aging

Wrinkle

Eligibility:

All Genders

22+ years

Phase:

NA

Brief Summary

To assess the safety, efficacy and patient satisfaction associated with the treatment of facial wrinkles using the Secret Micro-Needle Fractional RF System® (Ilooda Co., Ltd., Suwon, South Korea).

Detailed Description

Subjects satisfying all inclusion and exclusion criteria will be enrolled in this trial. After baseline evaluation, all subjects will undergo a series of 3 facial treatments with the Secret Micro-Need...

Eligibility Criteria

Inclusion

  • Males or females in good general health who are greater than 22 years of age.
  • Subjects may be of Fitzpatrick Skin Types I through VI.
  • Subjects must desire improvement of facial skin texture and wrinkling.
  • Subjects must have at least a score of 2 on the Fitzpatrick Wrinkle Scale evaluating the forehead, cheeks, and periorbital areas and Modified Fitzpatrick Wrinkle Scale evaluating the nasolabial folds (Appendix A1 and A2).
  • Subjects must be willing to provide written informed consent, HIPAA authorization, and photographic release.
  • Subjects must be willing to follow study instructions and complete all required visits.
  • Negative urine pregnancy test results at the time of study entry (if applicable).
  • The subject is healthy as judged by medical history and investigator's assessment of current health
  • Female subjects will be either of non-childbearing potential defined as:
  • 1\. Having no uterus. 2. No menses for at least 12 months. Or; (WOCBP) women of childbearing potential must agree to use an effective method of birth control during the course of the study, such as:
  • Oral contraceptive pill, injection, implant, patch, vaginal ring, intrauterine device (systemic birth control must have been started 30 days or more prior to enrolling)
  • Intrauterine coil
  • Bilateral tubal ligation
  • Barrier method used with an additional form of contraception (e.g., sponge, spermicide or condom)
  • Abstinence (If practicing abstinence must agree to use barrier method described above (4) if becomes sexually active).
  • Vasectomized partner (Must agree to use barrier method described above (4) if becomes sexually active with non-vasectomized).

Exclusion

  • A subject who has undergone treatment with any non-ablative laser, including IPL, within the last 3 months and any ablative laser within the last 6 months.
  • A subject who has undergone any microneedling treatment within the last 3 months
  • A subject with a history of previous fat transfer, injectable calcium hydroxylapatite or poly-l-lactic acid to the study area within the past 6 months.
  • A subject with a history of injection of hyaluronic acid dermal fillers in the study area within the past six months.
  • Retinoid, hydroquinone, microdermabrasion, or chemical peel treatments to the face within one month prior to study participation or during the study.
  • Current participation or participation within 30 days prior to the start of this study in a drug or other investigational research studies.
  • Presence of an active systemic or local skin disease that may affect wound healing.
  • Presence of scarring, sunburn, tattoos, open wounds or other skin condition in area to be treated that would interfere with the assessments of this study.
  • Individuals who have current skin cancers or suspicious lesions in the treatment area per Investigator.
  • Individuals who are nursing, pregnant, or planning to become pregnant during the study.
  • Patients who have a history with keloid formation or hypertrophic scarring.
  • Inability to understand the protocol or to give informed consent.
  • Subjects with deep dermal scarring or thick sebaceous skin of the treatment area.
  • History of impaired immune system, including but not limited to HIV, current malignancy.
  • History of chronic drug or alcohol abuse.
  • Current smoker or history of smoking in the last one year.
  • Subjects with known bleeding disorder or is receiving medication that will likely increase the risk of bleeding as the result of injection per investigator discretion.
  • Concurrent therapy that, in the investigator's opinion, would interfere with the evaluation of the safety or efficacy of the study device.
  • Subjects who anticipate the need for surgery or overnight hospitalization during the study.
  • Subjects who, in the investigator's opinion, have a history of poor cooperation, noncompliance with medical treatment, or unreliability.
  • History of using the following prescription medications:
  • Current use of psychiatric drugs that in the investigators opinion would impair the subject from understanding the protocol requirements or understanding and signing the informed consent.
  • Immunosuppressive medications.
  • Subjects with implantable cardiac devices, such as pacemakers or implantable cardioverter-defibrillators.

Key Trial Info

Start Date :

February 10 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 30 2019

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT03426098

Start Date

February 10 2018

End Date

June 30 2019

Last Update

May 10 2019

Active Locations (1)

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West Dermatology Research Center

San Diego, California, United States, 92121