Status:
COMPLETED
Effect of Smoking on the Expression of Gelatinases in Chronic Periodontitis
Lead Sponsor:
Baskent University
Conditions:
Periodontitis
Smoking
Eligibility:
All Genders
16-62 years
Brief Summary
This study comparatively evaluate the expressions of MMP-2 and MMP-9 in smoker vs non-smoker chronic periodontitis patients as well as periodontally healthy subjects. the hypothesis of this study was ...
Detailed Description
Smokers have greater risk for developing periodontal disease and smoking is highly correlated with greater marginal bone loss. Matrix metalloproteinases (MMP) play a major role in periodontal tissue d...
Eligibility Criteria
Inclusion
- A total of 80 subjects (35 females, 45 males, with an age range of 16-62 years) were included in this study from those patients seeking dental treatment at the Baskent University School of Dentistry between February 2010 and December 2012.
Exclusion
- Patients with systemic disease;
- pregnant and/or lactating women;
- patients taking any medications that may influence the study.
Key Trial Info
Start Date :
February 10 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 30 2012
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT03426241
Start Date
February 10 2010
End Date
December 30 2012
Last Update
February 8 2018
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