Status:
COMPLETED
The Effect of Intestinal Microbiota Transplantation for Inflammatory Bowel Diseases
Lead Sponsor:
Zhongshan Hospital Xiamen University
Conditions:
Inflammatory Bowel Disease(IBD)
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
There are many limitations in the current treatments of Inflammatory Bowel Diseases(IBD) which includes Ulcerative Colitis（UC) and Crohn's Disease(CD). Some patients have no or little reaction to the ...
Detailed Description
In this projects the investigators aim to re-establish a gut balance of intestinal microbiota through Standardized Intestinal Microbiota Transplantation for Ulcerative Colitis(UC) and Crohn's Disease(...
Eligibility Criteria
Inclusion
- Standard or conventional medicine treatment ineffective of Inflammatory Bowel Diseases(IBD) patients
- IBD patients with recurrent symptoms
- IBD patients who had drug dependence or recurrence when reduced or discontinued use
- Untreated IBD patients who voluntarily received Standardized Intestinal Microbiota Transplantation(IMT)
- Written informed consent/assent as appropriate
Exclusion
- IBD patients with contraindications for gastrointestinal endoscopy
- IBD patients with indication of surgery
- Moderate and severe renal injuty(serum creatinine\>2mg/dL or 177mmol/L), moderate and severe chronic obstructive pulmonary disease, severe hypertension, cerebrovascular accident, congestive heart failure, unstable angina pectoris
- Other serious diseases that may interfere the recruitment or affect the survival, such as cancer or acquired immune deficiency syndrome
- Mentally or legally disabled person
- Preparing for pregnancy
- Medical or social condition which in the opinion of the principal investigator would interfere with or prevent regular follow up
- Participating in other clinical trials.
Key Trial Info
Start Date :
November 21 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 30 2022
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT03426683
Start Date
November 21 2017
End Date
December 30 2022
Last Update
November 14 2023
Active Locations (1)
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1
Zhongshan Hospital Affiliated to Xiamen University
Xiamen, Fujian, China, 361000