Status:

COMPLETED

Comparison of 0.1 and 0.05mg Intrathecal Morphine for Post-cesarean Analgesia.

Lead Sponsor:

Medical University of South Carolina

Conditions:

Cesarean Section

Eligibility:

FEMALE

18+ years

Phase:

EARLY_PHASE1

Brief Summary

The purpose of this study is to determine the ideal dose of spinal morphine for use in Cesarean section. Spinal anesthesia (single injection in the lower back to numb patients from the waist down) is ...

Eligibility Criteria

Inclusion

  • any parturient 18 years of age or older
  • undergoing elective cesarean delivery under spinal anesthesia
  • able to consent to the study and participate in the follow-up.

Exclusion

  • any known allergy to morphine
  • general anesthesia
  • urgent or emergent cases
  • any bleeding diathesis or other coagulopathy
  • known G6PD deficiency
  • any known liver disease
  • known alcohol abuse or dependence
  • HELLP syndrome
  • thrombocytopenia or known platelet dysfunction
  • history or active gastrointestinal bleeding
  • acute kidney injury or chronic renal insufficiency
  • contraindication/refusal to spinal anesthestic
  • chronic pain
  • chronic narcotic use
  • illicit drug use
  • allergy to any study related medications

Key Trial Info

Start Date :

January 16 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 3 2023

Estimated Enrollment :

229 Patients enrolled

Trial Details

Trial ID

NCT03427463

Start Date

January 16 2018

End Date

August 3 2023

Last Update

December 19 2024

Active Locations (1)

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1

Medical University of South Carolina

Charleston, South Carolina, United States, 29425