Status:
UNKNOWN
the Effect of Calcium Dobesilate on Non Dialysis Patients With CKD
Lead Sponsor:
The Affiliated Hospital of Xuzhou Medical University
Conditions:
Chronic Renal Failure
Eligibility:
All Genders
18-75 years
Phase:
PHASE4
Brief Summary
To investigate the feasibility of calcium dobesilate in the treatment of microvascular injury provides new ideas and theoretical basis for the prevention and treatment of chronic renal failure.
Detailed Description
The deterioration of renal function is closely related to microvascular damage, calcium dobesilate is known as microcirculation protective agent, the investigators will further study its effect of non...
Eligibility Criteria
Inclusion
- Enroll the non dialysis patients with chronic renal failure hospitalized in the Department of Nephrology of the Affiliated Hospital of Xuzhou Medical University.
- According to the glomerular filtration rate, the patients who were not required to be dialysate were at CKD3-5 (GFR between 10 and 59ml/min).
Exclusion
- Exclude those patients with diabetes, cardiovascular disease, severe infection, shock, dehydration, abnormal liver function, received glucocorticoid therapy, surgery and emergency dialysis.
- Eliminate those patients with respiratory disease(such as chronic obstructive pulmonary disease, bronchiectasis, asthma), cardiovascular diseases(such as acute and chronic cardiac insufficiency), blood system diseases (such as aplastic anemia, nutritional anemia and polycythemia vera).
Key Trial Info
Start Date :
January 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2018
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03427944
Start Date
January 1 2015
End Date
December 31 2018
Last Update
February 14 2018
Active Locations (1)
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1
The Affiliated Hospital of Xuzhou Medical University
Xuzhou, Jiangsu, China, 221000