Status:
COMPLETED
Decrease Obstructive Sleep Apnea (OSA) Sympathetic Tone : Impact of APAP vs CPAP
Lead Sponsor:
University Hospital, Grenoble
Collaborating Sponsors:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
ResMed
Conditions:
Sleep Apnea Syndromes
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The present study aims to compare muscle sympathetic neural activity by microneurography after one month treatment of fixed versus auto-adjusting CPAP treatment and its impact on arterial blood pressu...
Detailed Description
Background: Sleep apnea syndrome (SAS) currently affects 10% of general population. It is characterized by the occurrence during the sleep of the upper airways closure which cause repeated asphyxia. I...
Eligibility Criteria
Inclusion
- patient with OSA (AHI ≥20 / h)
- patient with daytime sleepiness
- naive of any pressure treatment of OSA
- patient able to provide written informed consent
- not a vulnerable person or legally protected adult.
Exclusion
- pregnancy
- Person deprived of liberty or subject to a legal protection measure.
- Patient with serious heart failure (According to investigator judgment)
- patient with central sleep apnea index above 20% of AHI
- Patient with a significant intercurrent pathology that can influence the results. (According to investigator judgment).
Key Trial Info
Start Date :
March 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 30 2022
Estimated Enrollment :
57 Patients enrolled
Trial Details
Trial ID
NCT03428516
Start Date
March 1 2018
End Date
November 30 2022
Last Update
May 16 2024
Active Locations (1)
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1
CHU Grenoble Alpes
Grenoble, France, 38000