Status:

UNKNOWN

Study of microRNAs as a Diagnostic Tool for HCV-related Hepatocellular Carcinoma

Lead Sponsor:

HMHamed

Conditions:

miRna in HCC

Eligibility:

All Genders

20-80 years

Brief Summary

The aim of this work is to study the role of circulating miRNAs in diagnosis of HCV related hepatocellular carcinoma.

Detailed Description

Early diagnosis of hepatocellular carcinoma can significantly improve the overall survival of HCC patients, currently available diagnostic markers are still inadequate and limited by their low sensiti...

Eligibility Criteria

Inclusion

  • RNA extraction and quantitative Real-Time PCR analysis
  • Diagnosis of HCV will be based on detection of anti-HCV antibodies
  • Diagnosis of liver cirrhosis will be based on ultrasonography, biochemically and elastography when available
  • Diagnosis of HCC will be based on ultrasonography, the typical criteria in triphasic multislice CT scan

Exclusion

  • HBV or autoimmune or metabolic liver disease
  • serological evidence of human immunodeficiency virus (HIV) infection
  • malignancy in other organs
  • After intervention in treatment of hepatocellular carcinoma

Key Trial Info

Start Date :

February 15 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 1 2019

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT03429530

Start Date

February 15 2018

End Date

March 1 2019

Last Update

February 12 2018

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