Status:
UNKNOWN
The Effect of Exercise on Systemic Inflammation in Veterans With COPD and OSA
Lead Sponsor:
Salem Veterans Affairs Medical Center
Conditions:
COPD
OSA
Eligibility:
All Genders
Phase:
NA
Brief Summary
The overlap syndrome (OS), i.e. the association of both Chronic Obstructive Pulmonary Disease (COPD) and Obstructive Sleep Apnea (OSA) in a single Veteran, is prevalent and associated with increased c...
Detailed Description
The term "overlap syndrome" (OS) is used to describe the association of both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea disease (OSA) in a single Veteran. Given the high ...
Eligibility Criteria
Inclusion
- Veterans from the Salem VAMC pulmonary clinics will be screened for a diagnosis of OSA and treatment with CPAP therapy. In addition, an inclusion criterion also will be a recent PFT diagnostic of COPD (FEV1/FVC \<0.7 and FEV1\< 80%). Only Veterans with OS who are compliant with CPAP therapy will be enrolled in the study.
Exclusion
- orthopedic problems, fall-risk, balance problems;
- any regular participation in structured exercise sessions;
- other concomitant sleep disorder;
- unstable cardiovascular or pulmonary disease;
- acute infectious illness in the prior month;
- hospitalization in prior month;
- prescription of systemic glucocorticoids or immune-suppressive agents in the prior month and
- weight above 330 pounds, the limit allowed by the Wii pressure sensor floor mat.
Key Trial Info
Start Date :
December 5 2016
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2019
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT03431103
Start Date
December 5 2016
End Date
May 1 2019
Last Update
February 13 2018
Active Locations (1)
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1
Salem VAMC
Salem, Virginia, United States, 24153