Status:

UNKNOWN

Application of Forced Breath Technique While CPAP Therapy for Apnea Classification

Lead Sponsor:

Heinen und Löwenstein GmbH & Co. KG

Collaborating Sponsors:

Löwenstein Medical Technology

Conditions:

Sleep Apnea, Obstructive

Sleep Apnea, Central

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study analyzes the application of the Forced Breath Technique (FBT) to classify apneas during CPAP therapy with a prismaLAB (device name) therapy device. In this study the BiLevel ST (Spontaneou...

Detailed Description

Obstructive sleep-disordered breathing is usually treated by positive airway pressure (PAP) therapy with respective devices.The devices detect, classify and store respiratory events as apneas, hypopne...

Eligibility Criteria

Inclusion

  • diagnosis of sleep-disordered breathing (AHI \>= 15/h)
  • ensued or indicated CPAP titration within a routine PAP therapy setting
  • age \>= 18 years
  • presence of written informed consent
  • in case of therapy control or repeated participation: total number of apneas in the ensued treatment night was \> 10

Exclusion

  • written informed consent is missing
  • Participation in another clinical trial that influences the initiation of (auto) CPAP treatment by specifications of device settings or titration procedure
  • NYHA (New York Heart Association) class III or IV
  • acute cardiac decompensation
  • severe arrhythmia
  • severe hypotension, particularly in combination with intravascular volume depletion
  • severe epistaxis
  • high risk of barotrauma
  • decompensated pulmonary conditions
  • pneumothorax or pneumomediastinum
  • pneumocephalus
  • cranial trauma
  • status following brain surgery or surgical intervention on the pituitary gland or the middle/inner ear
  • acute sinus infection (sinusitis), middle ear infection (otitis media) or perforated eardrum
  • dehydration
  • Exclusion Criteria Statistical Evaluation:
  • Data of patients who completed the study protocol will be excluded from statistical analysis if one of the following criteria applies:
  • there is leakage of \> 50 l/min for
  • application of incorrect device settings
  • insufficient data quality of PSG (Polysomnography) -acquisition
  • the device was applied outside range of indication
  • data of diagnostic night are not acquired as a PSG
  • informed consent isn´t present
  • the total number of apneas during the treatment night with BiLevel ST is \< 10

Key Trial Info

Start Date :

March 24 2016

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 29 2018

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT03432910

Start Date

March 24 2016

End Date

March 29 2018

Last Update

February 14 2018

Active Locations (1)

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Page 1 of 1 (1 locations)

1

HELIOS Klinik

Hagen, North Rhine-Westphalia, Germany, 58091