Status:
UNKNOWN
Intrathecal Morphine and Local Infiltration Analgesia in Total Knee Arthroplasty
Lead Sponsor:
South Carelia Central Hospital
Conditions:
Pain, Postoperative
Eligibility:
All Genders
18-85 years
Phase:
PHASE4
Brief Summary
Double-blinded randomized control study investigating intrathecal morphine as an additive to spinal anesthesia in patients undergoing elective total knee arthroplasty. The investigators aim to include...
Eligibility Criteria
Inclusion
- elective primary total knee arthroplasty
- ASA I-III
- written consent
Exclusion
- rearthroplasty
- ASA IV-V
- inadequate spoken finnish for reliable pain assessment
- Dementia or otherwise impaired cognition
- contraindication for any medication or substance used in survey protocol
- weight \<50kg or BMI ≥35 kg/m2
- preoperative SpO2 less than 93%
- clinical suspicion that subject can not use PCA adequately
- history of substance abuse or current excessive use of alcohol
- preoperative use of either pregabalin, gabapentin or strong opiates
Key Trial Info
Start Date :
November 6 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2020
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT03434951
Start Date
November 6 2017
End Date
September 1 2020
Last Update
February 15 2018
Active Locations (1)
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1
South Carelia Central Hospital
Lappeenranta, Finland, 53130