Status:

UNKNOWN

Chemokine Receptor CXCR4-targeting Molecular Imaging for Metabolic Characterization of Multiple Myeloma and Lymphoma

Lead Sponsor:

Peking Union Medical College Hospital

Conditions:

Multiple Myeloma

Lymphoma

Eligibility:

All Genders

18+ years

Phase:

EARLY_PHASE1

Brief Summary

Chemokine receptor CXCR4 was expressed in MM and lymphoma cells and CXCR4-targeting molecular imaging- 68Ga-Pentixafor PET/CT could be a promising technique to evaluate the extent of MM and lymphoma w...

Detailed Description

Multiple myeloma: Multiple myeloma (MM) is characterized by the neoplastic proliferation of plasma cells producing a monoclonal immunoglobulin. The Durie and Salmon and ISS clinical staging system ha...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • suspected or confirmed untreated MM or lymphoma patients
  • 18F-FDG PET/CT within two weeks
  • signed written consent.
  • Exclusion criteria:
  • pregnancy
  • breastfeeding
  • known allergy against Pentixafor
  • any medical condition that in the opinion of the investigator,may significantly interfere with study compliance.

Exclusion

    Key Trial Info

    Start Date :

    June 1 2019

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 1 2020

    Estimated Enrollment :

    100 Patients enrolled

    Trial Details

    Trial ID

    NCT03436342

    Start Date

    June 1 2019

    End Date

    December 1 2020

    Last Update

    December 27 2019

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Department of Nuclear Medicine, Peking Union Medical College Hopital, Chinese Academy of Medical Science

    Beijing, China, 100730