Status:
UNKNOWN
Chemokine Receptor CXCR4-targeting Molecular Imaging for Metabolic Characterization of Multiple Myeloma and Lymphoma
Lead Sponsor:
Peking Union Medical College Hospital
Conditions:
Multiple Myeloma
Lymphoma
Eligibility:
All Genders
18+ years
Phase:
EARLY_PHASE1
Brief Summary
Chemokine receptor CXCR4 was expressed in MM and lymphoma cells and CXCR4-targeting molecular imaging- 68Ga-Pentixafor PET/CT could be a promising technique to evaluate the extent of MM and lymphoma w...
Detailed Description
Multiple myeloma: Multiple myeloma (MM) is characterized by the neoplastic proliferation of plasma cells producing a monoclonal immunoglobulin. The Durie and Salmon and ISS clinical staging system ha...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- suspected or confirmed untreated MM or lymphoma patients
- 18F-FDG PET/CT within two weeks
- signed written consent.
- Exclusion criteria:
- pregnancy
- breastfeeding
- known allergy against Pentixafor
- any medical condition that in the opinion of the investigator,may significantly interfere with study compliance.
Exclusion
Key Trial Info
Start Date :
June 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2020
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03436342
Start Date
June 1 2019
End Date
December 1 2020
Last Update
December 27 2019
Active Locations (1)
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1
Department of Nuclear Medicine, Peking Union Medical College Hopital, Chinese Academy of Medical Science
Beijing, China, 100730