Status:
COMPLETED
Treatment Response of Maintenance Dose of Proton Pump Inhibitor in Patients With Nonerosive Gatroesophageal Reflux Disease
Lead Sponsor:
Yonsei University
Conditions:
Non-erosive Gatroesophageal Reflux Disease
Eligibility:
All Genders
19-80 years
Phase:
NA
Brief Summary
For ERD(erosive reflux disease), which pathogenesis is mainly the acid reflux mechanism, primary treatment is therefore PPI. However, NERD(non-erosive reflux disease) is much more complex than ERD and...
Detailed Description
(1) Among GERD patients, EGD(esophagogastroduodenoscopy) must be done before 6 months and must prove there is no erosive lesion. (2) During EGD, esophagus mucosa histology will be taken for evaluation...
Eligibility Criteria
Inclusion
- Patient over 19 years old
- Patient with typical GERD symptom (heartburn or acid reflux more than once a week)
Exclusion
- Patient who received EGD since the past 6 months, and diagnosed as GERD endoscopically
- Patient with active gastric/duodenal ulcer
- Patient who received esophagus, stomach or duodenum surgery
- Patient with hypersensitivity to esomezol®
- Patient with no achieved agreement on the study from the guardian or patient himself.
Key Trial Info
Start Date :
September 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 18 2019
Estimated Enrollment :
62 Patients enrolled
Trial Details
Trial ID
NCT03436914
Start Date
September 1 2018
End Date
October 18 2019
Last Update
January 2 2020
Active Locations (1)
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1
Yonsei university College of Medicine
Seoul, South Korea, 03722