Status:
RECRUITING
Alternation in the Human Microbiome With Commonly Used Topical Medications
Lead Sponsor:
University of California, Davis
Conditions:
Healthy
Eligibility:
All Genders
18+ years
Phase:
PHASE1
Brief Summary
The global aim of this study is to investigate how the human microbiome changes from baseline with commonly used topical medications such as topical antifungals, low to mid potency topical steroids an...
Detailed Description
The microorganisms present on human skin influence human health and disease. Older methods of studying the skin microbiota, such as culture based techniques, favored bacteria, which readily grew under...
Eligibility Criteria
Inclusion
- The inclusion criteria:
- • Adults at least 18 years of age.
- The exclusion criteria:
- Individuals with known chronically active skin diseases, including atopic dermatitis, psoriasis, seborrheic dermatitis, other autoimmune and inflammatory skin conditions.
- Patients with a history of skin cancer, multiple nevi, or other isolated lesions will not be excluded.
- Individuals who have used topical, intravenous, intramuscular, or oral antibiotics within the last 6 months
- Individuals with known allergies to any of the study medications.
- Individuals younger than 18 years of age.
- Adults unable to consent
- Non-English speaking individuals. Given the complexity in the instructions that subjects will need to follow for proper sample collection, we will not seek to recruit non-English speaking individuals for this pilot study.
- Prisoners
Exclusion
Key Trial Info
Start Date :
January 28 2013
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 28 2026
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT03437005
Start Date
January 28 2013
End Date
September 28 2026
Last Update
February 7 2025
Active Locations (1)
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1
University of California, Davis, Department of Dermatology
Sacramento, California, United States, 95816